Dec 04, 2022  
2020-2021 Academic Catalog 
    
2020-2021 Academic Catalog [Published Catalog]

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GHHE 000/5430 - Integrating Biomarkers in Population‐based Research (3 cr.)



Description
Biomarkers are increasingly used in population-based research, with varying success. On the plus side, they tend to be quantitative and relatively objective measures of an important exposure, covariate, or intermediate marker of disease. However, their pitfalls are often poorly appreciated, and frequently ignored. This course surveys the major issues relevant to the application of biomarkers in epidemiological research, including the logistical hurdles in biospecimen collection and storage, a critical assessment of biomarker quality, the interpretation of quantitative estimates, and the resultant analytic issues that often arise in statistical analysis. After taking this course, students should understand the important issues to consider in planning a molecular epidemiological study, and be able to critically assess the literature linking biomarkers to health endpoints.



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